hydralazine hcl drug class

A direct-acting vasodilator that is used as an antihypertensive agent. C 8 H 8 N 4 HCl MW.

1 Drugs Acting On Cardiovascular System

A class of drugs is a group of medications that work in a similar way.

. Usual maintenance 5075 mg 4 times a day. Hydralazine has been linked to several forms of acute liver injury as well as a lupus-like syndrome. Hydralazine is in a class of medications called vasodilators.

The exact mechanism of how hydralazine causes arterial smooth muscle relaxation is not yet understood. Apresoline belongs to a class of drugs called Vasodilators. Signs and symptoms of lupus usually regress when the drug is discontinued.

It is a peripheral arterial vasodilator and causes relaxation of blood vessels which carry blood away from the heart and towards the organs and tissues. What Are Side Effects of Apresoline. Save up to 80 today.

Apresoline hydralazine hydrochloride USP is an antihypertensive available as 10- 25- 50- and 100-mg tablets for oral administration. Select TryBuy and follow instructions to begin your free 30-day trial. Fulminant hepatic failure caused by ecarazine hydrochloride a hydralazine.

Name Hydralazine hydrochloride Drug Entry Hydralazine. Per JNC 8 guidelines it is not a first-line agent for the treatment of essential hypertension. Positive direct Coombs tests in patients with hydralazine-induced SLE.

High blood pressure adds to the workload of the heart and arteries. 15 Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure. 17187 N Laurel Park Dr Ste 300 Livonia MI 48152-2600.

Taking oral hydralazine with food improves the bioavailability of the drug. 14 The C max of oral hydralazine is 012-131µM depending on the acetylator status of patients. Side effects of Apresoline include.

Hydralazine Apresoline is an antihypertensive medication used to treat high blood pressure. It has been found to be particularly useful in heart failure together with isosorbide dinitrate for treatment of people of African descent. Hydralazine is used with or without other medications to treat high blood pressure.

Hydralazine is the 1-hydrazino derivative of phthalazine. You can cancel anytime within the 30-day trial or continue using Daviss Drug Guide to begin a 1-year subscription 3995 hydrALAZINE. Nasal congestion muscle cramps SLE-like syndrome fixed drug eruption edema.

These drugs are often used to treat similar conditions. 14 Volume of distribution. Hydralazine has been linked to several forms of acute liver injury as well as a lupus-like syndrome.

It has a role as an antihypertensive agent and a vasodilator agent. Adult Initially 25 mg 34 times a day subsequent doses to be increased every 2 days if necessary. Ad Whether you need prescription savings or a virtual doctors appointment we can help.

Other drugs in class Other drugs in class Vasodilator. Find patient medical information for hydralazine HCl bulk on WebMD including its uses side effects and safety interactions pictures warnings and user ratings. Chest pain fast heart rate.

This is not a complete list of side effects and others may occur. Hydralazine side effects more detail. Its chemical name is 1-hydrazinophthalazine.

Nausea vomiting diarrhea loss of appetite. Compare prescription prices and save instantly with a free coupon. Symptoms and signs usually regress when the drug is discontinued but residua have been detected many years later.

The volume of distribution is. Hydralazine is used to treat high blood pressure hypertension. Lowering high blood pressure helps prevent strokes heart attacks.

However residual signs and symptoms have been detected many years later. This includes high blood pressure in pregnancy and very high blood pressure resulting in symptoms. It is a member of phthalazines an azaarene an.

Chest pain or pressure. Download the Daviss Drug Guide app by Unbound Medicine. Hydralazine is used to treat high blood pressure.

It is soluble in water slightly soluble in alcohol and very. Hydralazine is a commonly used oral antihypertensive agent that acts by inducing peripheral vasodilation. This is due to hydralazines stimulation of the sympathetic nervous system.

Call your doctor for medical advice about side effects. Each tablet for oral administration contains 10 mg 25 mg 50 mg or 100 mg hydralazine hydrochloride USP. Hydralazine sold under the brand name Apresoline among others is a medication used to treat high blood pressure and heart failure.

It melts at about 275C with decomposition. High blood pressure is a common condition and when not treated can cause damage to the brain heart blood vessels kidneys and other parts. You may report side effects to FDA at 1-800-FDA-1088.

Hydralazine interferes with urinary 17-OHCS determinations modified Glenn-Nelson technique. It is soluble in water slightly soluble in alcohol. It works by relaxing the blood vessels so that blood can flow more easily through the body.

Heart failure with long acting nitrate initiated in hospital or under specialist supervision for hydralazine hydrochloride By mouth. If hydralazine-induced SLE occurs the drug should be discontinued unless the benefit of continued antihypertensive therapy with this drug outweighs the risk. Hydralazine hydrochloride USP is a white to off-white odorless crystalline powder.

Hydralazine is a direct vasodilator used orally to treat essential hypertension among other diseases and intravenously to rapidly reduce blood pressure in hypertensive urgency or emergency. 13 An intravenous dose of 03mgkg leads to an AUC of 175-294µMmin and a 1mgkg oral dose leads to an AUC of 40-304µMmin. Originally developed in the 1950s as a malaria treatment hydralazine showed antihypertensive ability and was soon repurposed.

Hydralazine Hydrochloride USP is a white to off-white odorless crystalline powder. Requires continued antihypertensive therapy with this drug. Common side effects may include.

Hydralazine belongs to a class of drugs called peripheral vasodilators. It is also used to control high blood pressure in a mother during pregnancy pre-eclampsia or eclampsia or in emergency situations when blood pressure is extremely high hypertensive crisis.

Synthesis Of Hydralazine